Haematological abnormalities in neonatal necrotizing enterocolitis.
نویسندگان
چکیده
OBJECTIVE Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in preterm infants born prior to 32 weeks gestation or with a birth weight less than 1500 grams. In this article, we review hematological abnormalities associated with NEC. METHODS A literature search was performed using the databases PubMed, EMBASE, and Scopus, and the electronic archive of abstracts presented at the annual meetings of the Pediatric Academic Societies. RESULTS Thrombocytopenia, disseminated intravascular coagulation, increased or decreased neutrophil counts, and hemolytic anemia are frequent events in NEC. CONCLUSIONS NEC is associated with several hematological abnormalities, which may play a direct or indirect role in the pathogenesis of gut mucosal injury, and may also carry important prognostic information.
منابع مشابه
Neonatal Perforated Appendicitis Masquerading as Necrotizing Enterocolitis
A preterm neonate underwent emergent laparotomy for presumed necrotizing enterocolitis (NEC). Intra-operatively, neonatal perforated appendicitis (NPA) was encountered. This may represent a form of NEC localized to the appendix. A high index of clinical suspicion and early laparotomy are recommended.
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31 Jackman S, Brereton RJ, Wright VM. Results of surgical treatment of neonatal necrotizing enterocolitis. BrJ Surg 1990, 77: 146-8. 32 Smith SD, Tagge EP, Miller J, Cheu H, Sukarochana K, Rowe MI. The hidden mortality in surgically treated necrotizing enterocolitis: fungal sepsis. J Pediatr Surg 1990; 25: 1030-3. 33 Cikrit D, Mastandrea J, West KW, Schreiner RL, Grosfeld JL. Necrotizing entero...
متن کاملSurgical management of neonatal necrotising enterocolitis
31 Jackman S, Brereton RJ, Wright VM. Results of surgical treatment of neonatal necrotizing enterocolitis. BrJ Surg 1990, 77: 146-8. 32 Smith SD, Tagge EP, Miller J, Cheu H, Sukarochana K, Rowe MI. The hidden mortality in surgically treated necrotizing enterocolitis: fungal sepsis. J Pediatr Surg 1990; 25: 1030-3. 33 Cikrit D, Mastandrea J, West KW, Schreiner RL, Grosfeld JL. Necrotizing entero...
متن کاملProbiotic Use for the Prevention of Necrotizing Enterocolitis in Preterm Infants
Necrotizing enterocolitis (NEC) is among the most common and devastating diseases that primarily afflicts preterm infants in neonatal intensive care units (NICU) (1). Despite recent advances in neonatal care, the incidence of necrotizing enterocolitis and the associated morbidity and mortality have remained unchanged because of the improved survival for smaller, more premature infants (2). Both...
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عنوان ژورنال:
- The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
دوره 25 Suppl 4 شماره
صفحات -
تاریخ انتشار 2012